Pancreas Transplant Research Today is a free monthly online journal that collates and summarizes the latest research about Pancreas Transplant, including details on risks, prognosis, procedure, surgery, organ donation. | ||||||||
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Organogenesis of the endocrine pancreas.Hammerman MR Renal Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. mhammerm@wustl.edu Organogenesis of the endocrine pancreas. Embryonic pancreatic primordia transplanted into diabetic animal hosts undergo selective endocrine differentiation in situ and normalize glucose tolerance. Pancreatic primordia can be transplanted across isogeneic, allogeneic, and both concordant (rat to mouse) and highly disparate (pig to rodent) xenogeneic barriers. This review explores the therapeutic potential for pancreatic organogenesis posttransplantation of embryonic primordia. Published 13 October 2005 in Kidney Int, 68(5): 1953-5.
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